Quantum computers might eventually be able to handle some AI applications that currently require huge amounts of conventional computing power. Such a development would be a major boost to machine learning and similar artificial intelligence algorithms. Quantum computers hold the promise of eventually being able to complete certain calculations that are impossible for conventional computers. For years, researchers have been debating whether these advantages over conventional computers extend to tasks that involve lots of data, and the algorithms that learn from them - in other words, the machine learning that underlies many AI programs. Now, Hsin-Yuan Huang at the quantum computing firm Oratomic and his colleagues argue that the answer ought to be "yes". Their mathematical work aims to lay the foundations for a future where quantum computers offer a broad boost to AI. "Machine learning is really utilised everywhere in science and technology and also everyday life.

Background: Single-cell RNA sequencing (scRNA-seq) enables gene expression profiling at cellular resolution but is inherently affected by sparsity caused by dropout events, where expressed genes are recorded as zeros due to technical limitations. These artifacts distort gene expression distributions and compromise downstream analyses. Numerous imputation methods have been proposed to recover latent transcriptional signals. These methods range from traditional statistical models to deep learning (DL)-based methods. However, their comparative performance remains unclear, as existing benchmarks evaluate only a limited subset of methods, datasets, and downstream analyses. Results: We present a comprehensive benchmark of 15 scRNA-seq imputation methods spanning 7 methodological categories, including traditional and DL-based methods. Methods are evaluated across 30 datasets from 10 experimental protocols on 6 downstream analyses. Results show that traditional methods, such as model-based, smoothing-based, and low-rank matrix-based methods, generally outperform DL-based methods, including diffusion-based, GAN-based, GNN-based, and autoencoder-based methods. In addition, strong performance in numerical gene expression recovery does not necessarily translate into improved biological interpretability in downstream analyses, including cell clustering, differential expression analysis, marker gene analysis, trajectory analysis, and cell type annotation. Furthermore, method performance varies substantially across datasets, protocols, and downstream analyses, with no single method consistently outperforming others. Conclusions: Our findings provide practical guidance for selecting imputation methods tailored to specific analytical objectives and underscore the importance of task-specific evaluation when assessing imputation performance in scRNA-seq data analysis.

In optimization problems, some variable subsets may have a joint non-linear or non-monotonical influence on the function value. Therefore, knowledge of variable dependencies may be crucial for effective optimization, and many state-of-the-art optimizers leverage it to improve performance. However, some real-world problem instances may be the subject of noise of various origins. In such a case, variable dependencies relevant to optimization may be hard or impossible to tell using dependency checks sufficient for problems without noise, making highly effective operators, e.g., Partition Crossover (PX), useless. Therefore, we use Statistical Linkage Learning (SLL) to decompose problems with noise and propose a new SLL-dedicated mask construction algorithm. We prove that if the quality of the SLL-based decomposition is sufficiently high, the proposed clustering algorithm yields masks equivalent to PX masks for the noise-free instances. The experiments show that the optimizer using the proposed mechanisms remains equally effective despite the noise level and outperforms state-of-the-art optimizers for the problems with high noise.

The framework of centralized training with decentralized execution (CTDE) [8,28]isone ofthe popular frameworks for solving cooperative multi-agent tasks.

This makes CDE particularly useful in critical application domains. However, interpretable CDE methods are understudied.

We decreased the confidence threshold to 0.1 to increase article and headline The following specifications were used: { resolution: 256, learning rate: 2e-3 }. This limit is binding for common words, e.g., "the". The recognizer is trained using the Supervised Contrastive ("SupCon") loss function [7], a gener-45 In particular, we work with the "outside" SupCon loss formulation We use a MobileNetV3 (Small) encoder pre-trained on ImageNet1k sourced from the timm [19] We use 0.1 as the temperature for Center Cropping, to avoid destroying too much information. C (Small) model that is developed in [2] for character recognition. If multiple article bounding boxes satisfy these rules for a given headline, then we take the highest.

ImageNet-100 is a subset of 100 categories from the coarse-grained ImageNet [13] dataset.